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Index > Protein center > Bin1(Gene name) > Mouse
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  • Bin1 (Gene name),
  • Myc box-dependent-interacting protein 1 (Protein name ),  BIN1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Bin1(Amphl;Sh3p9);
    Protein name:
    Myc box-dependent-interacting protein 1;
    Alternative:
    Amphiphysin-like protein;Amphiphysin II;SH3 domain-containing protein 9;Bridging integrator 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer with AMPH (By similarity). Interacts (via SH3 domain) with SYNJ1. Interacts (via SH3 domain) with DNM1. Interacts with CLTC. Interacts with AP2A2. Interacts with AP2B1. Interacts with MYC (via N-terminal transactivation domain); the interaction requires the integrity of the conserved MYC box regions 1 and 2. Binds SH3GLB1. Interacts with BIN2.
    Function:
    May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    588
    Sequence:
    50:
    MAEMGSKGVT | AGKIASNVQK | KLTRAQEKVL | QKLGKADETK | DEQFEQCVQN | 
    100:
    FNKQLTEGTR | LQKDLRTYLA | SVKAMHEASK | KLSECLQEVY | EPEWPGRDEA | 
    150:
    NKIAENNDLL | WMDYHQKLVD | QALLTMDTYL | GQFPDIKSRI | AKRGRKLVDY | 
    200:
    DSARHHYESL | QTAKKKDEAK | IAKPVSLLEK | AAPQWCQGKL | QAHLVAQTNL | 
    250:
    LRNQAEEELI | KAQKVFEEMN | VDLQEELPSL | WNSRVGFYVN | TFQSIAGLEE | 
    300:
    NFHKEMSKLN | QNLNDVLVSL | EKQHGSNTFT | VKAQPSDNAP | EKGNKSPSPP | 
    350:
    PDGSPAATPE | IRVNHEPEPA | SGASPGATIP | KSPSQLRKGP | PVPPPPKHTP | 
    400:
    SKEMKQEQIL | SLFDDAFVPE | ISVTTPSQFE | APGPFSEQAS | LLDLDFEPLP | 
    450:
    PVASPVKAPT | PSGQSIPWDL | WEPTESQAGI | LPSGEPSSAE | GSFAVAWPSQ | 
    500:
    TAEPGPAQPA | EASEVVGGAQ | EPGETAASEA | TSSSLPAVVV | ETFSATVNGA | 
    550:
    VEGSAGTGRL | DLPPGFMFKV | QAQHDYTATD | TDELQLKAGD | VVLVIPFQNP | 
    588:
    EEQDEGWLMG | VKESDWNQHK | ELEKCRGVFP | ENFTERVQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    E8983m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    E8983r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    E8983h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    U8983h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    U8983m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    U8983r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    P8983Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Myc box-dependent-interacting protein 1
    Cat.:
    P8983Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Myc box-dependent-interacting protein 1
    Monoclonal Antibody for Mouse Myc box-dependent-interacting protein 1
    Monoclonal Antibody for Mouse Myc box-dependent-interacting protein 1
    Monoclonal Antibody for Mouse Myc box-dependent-interacting protein 1
    Protein for Mouse Myc box-dependent-interacting protein 1
    Protein for Mouse Myc box-dependent-interacting protein 1
    Protein for Mouse Myc box-dependent-interacting protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A new member of the amphiphysin family connecting endocytosis and signal transduction pathways."
      Leprince C. , Romero F. , Cussac D. , Vayssiere B. , Berger R. , Tavitian A. , Camonis J.H.
      J. Biol. Chem.272:15101-15105(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: BALB/c.
      tissue: Brain.
    2. 2.
      "Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins."
      Sparks A.B. , Hoffman N.G. , McConnell S.J. , Fowlkes D.M. , Kay B.K.
      Nat. Biotechnol.14:741-744(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Embryo.
    3. 3.
      "Characterization of endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1."
      Modregger J. , Schmidt A.A. , Ritter B. , Huttner W.B. , Plomann M.
      J. Biol. Chem.278:4160-4167(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SH3GLB1
    4. 4.
      "Phosphoproteomic analysis of the developing mouse brain."
      Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
      Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic brain.
    5. 5.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    6. 6.
      "Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations."
      Munton R.P. , Tweedie-Cullen R. , Livingstone-Zatchej M. , Weinandy F. , Waidelich M. , Longo D. , Gehrig P. , Potthast F. , Rutishauser D. , Gerrits B. , Panse C. , Schlapbach R. , Mansuy I.M.
      Mol. Cell. Proteomics6:283-293(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain cortex.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-296; SER-298; SER-304 AND THR-308;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    8. 8.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-332;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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